Calgranulin A
Synonyms
60B8 B Antigen
60B8-B Antigen
A8 Protein, S100
Antigen, 60B8-B
Antigen, Cystic Fibrosis
CABP-P8
Cystic Fibrosis Antigen
Leukocyte L1 Protein Light Chain
MRP 8 Protein
MRP-8 Protein
MRP8 Protein
Macrophage Related Protein 8
Macrophage-Related Protein-8
Myeloid Calcium Binding Protein P8
Myeloid Calcium-Binding Protein P8
S100 A8 Protein
S100A8 Protein
A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.