Calreticulin
Synonyms
55 kDa High Affinity Calcium Binding Protein
55-kDa High-Affinity Calcium Binding Protein
CAB-63
CBP3 (Liver)
Calcium Binding Protein 3
Calcium-Binding Protein-3
Calregulin
ERp60
HACBP
cC1qR Protein
A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.