Caspase 2
Synonyms
Caspase 2 Subunit p12
Caspase 2 Subunit p13
Caspase 2 Subunit p18
Caspase-2
ICH 1 Protease
ICH-1 Protease
Pro Caspase 2
Pro-Caspase-2
Procaspase 2
Procaspase-2
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.