Cerebral Amyloid Angiopathy
Synonyms
Amyloid Angiopathy, Cerebral
Angiopathy, Cerebral Amyloid
Angiopathy, Congophilic
Cerebral Amyloid Angiopathies
Congophilic Angiopathies
Congophilic Angiopathy
Sporadic Cerebral Amyloid Angiopathy
A heterogeneous group of sporadic or familial disorders characterized by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES. Clinical features include multiple, small lobar CEREBRAL HEMORRHAGE; cerebral ischemia (BRAIN ISCHEMIA); and CEREBRAL INFARCTION. Cerebral amyloid angiopathy is unrelated to generalized AMYLOIDOSIS. Amyloidogenic peptides in this condition are nearly always the same ones found in ALZHEIMER DISEASE. (from Kumar: Robbins and Cotran: Pathologic Basis of Disease, 7th ed., 2005)