Cholesterol 7-alpha-Hydroxylase
Synonyms
CYP 7
CYP 7A
CYP7
CYP7A
Cholesterol 7 Hydroxylase
Cholesterol 7 alpha Hydroxylase
Cholesterol 7 alpha Monooxygenase
Cholesterol 7-alpha-Monooxygenase
Cholesterol 7alpha Hydroxylase
Cholesterol 7alpha-Hydroxylase
Cholesterol,NADPH:oxygen oxidoreductase (7 alpha-hydroxylating)
Cholesterol-7-Hydroxylase
Cytochrome P 450 CYP7
Cytochrome P-450 CYP7
Cytochrome P450 7
A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.