Cytochrome P-450 CYP1A1
Synonyms
7-Ethoxyresorufin O-Deethylase
CYP 1A1
CYP1A1
CYP1A1 Protein
Cytochrome P 450 CYP1A1
Cytochrome P450 IA1
EROD
Ethoxyresorufin Dealkylase
Ethoxyresorufin O-Deethylase
Ethylresorufin O-Deethylase
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.