Cytochrome P-450 CYP2B1
Synonyms
7 Benzyloxyresorufin O Dealkylase
7 Pentylresorufin O Depentylase
7-Benzyloxyresorufin O-Dealkylase
7-Pentylresorufin O-Depentylase
BROD
Benzyloxyresorufin O Dealkylase
Benzyloxyresorufin O-Dealkylase
CYP 2B1
CYP2B1
Cytochrome P 450 CYP2B1
Cytochrome P450 2B1
O-Dealkylase, Pentoxyresorufin
PROD
Pentoxyresorufin O Dealkylase
Pentoxyresorufin O-Dealkylase
A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.