Factor VIIIa
Synonyms
Activated Factor VIII
Blood Coagulation Factor VIII, Activated
Blood-coagulation factor VIIIa, procoagulant
Coagulation Factor VIIIa
Factor VIII, Activated
Factor VIII, Thrombin Activated
Factor VIII, Thrombin-Activated
Factor VIIIa Heavy Chain, 200 kDa Isoform
Factor VIIIa Heavy Chain, 92 kDa Isoform
Factor VIIIa Light Chain
Factor VIIIa, Coagulation
Thrombin-Activated Factor VIII
VIIIa, Coagulation Factor
Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va.
See Also