Floxuridine

Synonyms

5 Fluorodeoxyuridine

5-FUdR

5-Fluorodeoxyuridine

FUdR

Fluorodeoxyuridine

Uridine, 2'-deoxy-5-fluoro-

An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.