Genes, Retinoblastoma
Synonyms
Gene, Rb
Gene, Retinoblastoma
Genes, Rb
Rb Gene
Rb Genes
Retinoblastoma Gene
Retinoblastoma Genes
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.
See Also