Glutaredoxins
Synonyms
Glutaredoxin
Glutaredoxin 1
Glutaredoxin 2
Glutaredoxin 3
Glutaredoxin 5
TTase 1
TTase-1
Thioltransferase
Thioltransferase 1
Thioltransferase-1
A family of thioltransferases that contain two active site CYSTEINE residues, which either form a disulfide (oxidized form) or a dithiol (reduced form). They function as an electron carrier in the GLUTHIONE-dependent synthesis of deoxyribonucleotides by RIBONUCLEOTIDE REDUCTASES and may play a role in the deglutathionylation of protein thiols. The oxidized forms of glutaredoxins are directly reduced by the GLUTATHIONE.