Glycyrrhizic Acid

Synonyms

Acid, Glycyrrhizic

Acid, Glycyrrhizinic

Diammonium Glycyrrhizinate

Dipotassium Glycyrrhizinate

Glycyrrhizate, Zinc

Glycyrrhizin

Glycyrrhizinate, Diammonium

Glycyrrhizinate, Dipotassium

Glycyrrhizinic Acid

Zinc Glycyrrhizate

alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-

A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.