Granulomatous Disease, Chronic

Synonyms

Autosomal Recessive Chronic Granulomatous Disease

Chronic Granulomatous Disease

Chronic Granulomatous Disease, Atypical

Chronic Granulomatous Disease, X Linked

Chronic Granulomatous Disease, X-Linked

Chronic Granulomatous Diseases

Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked

Cytochrome B-Positive Granulomatous Disease, Chronic, X-Linked

Granulomatous Disease, Chronic, X-Linked

Granulomatous Disease, Chronic, X-Linked, Variant

Granulomatous Diseases, Chronic

X Linked Chronic Granulomatous Disease

X-Linked Chronic Granulomatous Disease

A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.