GRB2 Adaptor Protein
Synonyms
Abundant Src Homology Protein
GRB2 Adaptor Protein, Grb3 3 Isoform
GRB2 Adaptor Protein, Grb3-3 Isoform
Grb3-3 Adaptor Protein
Growth Factor Receptor Bound Protein 2
Growth Factor Receptor-Bound Protein-2
A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS).