Receptor, Epidermal Growth Factor
Synonyms
EGF Receptor
Epidermal Growth Factor Receptor
Epidermal Growth Factor Receptor Kinase
Epidermal Growth Factor Receptor Protein Tyrosine Kinase
Epidermal Growth Factor Receptor Protein-Tyrosine Kinase
ErbB-1 Receptor
Protein, Proto-oncogene c-ErbB-1
Proto oncogene c ErbB 1 Protein
Proto-Oncogene Protein, erbB-1
Proto-oncogene c-ErbB-1 Protein
Receptor, EGF
Receptor, ErbB 1
Receptor, ErbB-1
Receptor, TGF alpha
Receptor, TGF-alpha
Receptor, Transforming Growth Factor alpha
Receptor, Transforming-Growth Factor alpha
Receptor, Urogastrone
Resceptor Tyrosine protein Kinase erbB 1
Resceptor Tyrosine-protein Kinase erbB-1
TGF-alpha Receptor
Transforming Growth Factor alpha Receptor
Urogastrone Receptor
c erbB 1 Protein
c-ErbB-1 Protein, Proto-oncogene
c-erbB-1 Protein
erbB 1 Proto Oncogene Protein
erbB-1 Proto-Oncogene Protein
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
See Also