Heparin-binding EGF-like Growth Factor

Synonyms

Diphtheria Toxin Receptor

Diphtheria Toxin Receptors

HB EGF

HB EGF Precursor

HB-EGF

HB-EGF Precursor

HB-EGF, Short Form

Heparin binding EGF like Growth Factor

Heparin binding Epidermal Growth Factor like Growth Factor Precursor Protein

Heparin-binding EGF-like Growth-Factor

Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein

Receptor, Diphtheria Toxin

Receptors, Diphtheria Toxin

SF HB EGF

SF HB-EGF

Short Form HB EGF

Short Form HB-EGF

Toxin Receptor, Diphtheria

Toxin Receptors, Diphtheria

An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.