Laron Syndrome
Synonyms
Dwarfism II, Pituitary
Dwarfism IIs, Pituitary
Dwarfism, Laron
GH Resistance, Primary
Growth Hormone Insensitivity Syndrome
Growth Hormone Receptor Defect
Growth Hormone Receptor Deficiency
Laron Dwarfism
Laron Type Dwarfism I
Pituitary Dwarfism II
Pituitary Dwarfism IIs
Primary GH Resistance
Primary Growth Hormone Resistance
Severe GH Insensitivity
Syndrome, Laron
An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.