Mannose-Binding Protein-Associated Serine Proteases
Synonyms
MASP Proteases
MASP Related Protein
MASP-Related Protein
MASPs
MBL Associated Serine Proteases
MBL-Associated Serine Proteases
MBP Associated Serine Protease
MBP Associated Serine Protease Related Protein
MBP-Associated Serine Protease
MBP-Associated Serine Protease-Related Protein
Mannan Binding Lectin Serine Proteases
Mannan-Binding Lectin Serine Proteases
Mannose Binding Protein Associated Serine Protease
Mannose-Binding Protein-Associated Serine Protease
Proteases, MASP
Protein, MASP-Related
Serine Protease, MBP-Associated
Serine Proteases, MBL-Associated
Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.