Marchiafava-Bignami Disease
Synonyms
Marchiafava Bignami Disease
Marchiafava Bignami Syndrome
Marchiafava-Bignami Syndrome
A neurodegenerative condition that is characterized by demyelination or necrosis of the CORPUS CALLOSUM. Symptoms include DEPRESSION; PARANOIA; DEMENTIA; SEIZURES; and ATAXIA which can progress to COMA and death in a few months. Marchiafava-Bignami syndrome is seen often in alcoholics but has been found in non-alcoholics as well.