Mecamylamine

Synonyms

Bicyclo(2.2.1)heptan-2-amine, N,2,3,3-tetramethyl-

A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.