Muscimol

Synonyms

3(2H)-Isoxazolone, 5-(aminomethyl)-

Agarin

Pantherine

A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.