Optic Atrophy, Autosomal Dominant
Synonyms
Atrophies, Juvenile Optic
Atrophies, Kjer-Type Optic
Atrophy, Juvenile Optic
Atrophy, Kjer's Optic
Atrophy, Kjer-Type Optic
Autosomal Dominant Optic Atrophy
Autosomal Dominant Optic Atrophy Kjer Type
Dominant Optic Atrophies
Dominant Optic Atrophy
Juvenile Optic Atrophies
Juvenile Optic Atrophy
Kjer Optic Atrophy
Kjer Type Optic Atrophy
Kjer's Optic Atrophy
Kjer-Type Optic Atrophies
Kjer-Type Optic Atrophy
Kjers Optic Atrophy
Optic Atrophies, Dominant
Optic Atrophies, Juvenile
Optic Atrophies, Kjer-Type
Optic Atrophy 1
Optic Atrophy 1s
Optic Atrophy Type 1
Optic Atrophy, Dominant
Optic Atrophy, Hereditary, Autosomal Dominant
Optic Atrophy, Juvenile
Optic Atrophy, Kjer Type
Optic Atrophy, Kjer's
Optic Atrophy, Kjer-Type
Dominant optic atrophy is a hereditary optic neuropathy causing decreased visual acuity, color vision deficits, a centrocecal scotoma, and optic nerve pallor (Hum. Genet. 1998; 102: 79-86). Mutations leading to this condition have been mapped to the OPA1 gene at chromosome 3q28-q29. OPA1 codes for a dynamin-related GTPase that localizes to mitochondria.