Peptide Elongation Factor Tu
Synonyms
EF Tu
EF-Tu
Elongation Factor Tu
Eucaryotic Elongation Factor Tu
Factor Tu, Elongation
Protein Synthesis Elongation Factor Tu
eEF Tu
eEF-Tu
A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.