Phosphatidylinositol 4,5-Diphosphate

Synonyms

4,5-Biphosphate, Phosphatidylinositol

4,5-Diphosphate, Phosphatidylinositol

Phosphatidylinositol 4,5 Biphosphate

Phosphatidylinositol 4,5 Diphosphate

Phosphatidylinositol 4,5-Biphosphate

Phosphatidylinositol Phosphate, PtdIns(4,5)P2

Phosphatidylinositol-4,5-Biphosphate

PtIns 4,5-P2

PtdIns(4,5)P2

PtdInsP

PtdInsP2

A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)