Phosphofructokinase-2
Synonyms
6-PF-2-K-Fru-2,6-P(2)ase
6-Phosphofructo 2-kinase-fructose 2,6-bisphosphatase
6-Phosphofructo-2-kinase
6-Phosphofructo-2-kinase-fructose-2,6-bisphosphatase
6PF2K
ATP-D-Fructose-6-phosphate 2-phosphotransferase
F Kinase-F-bisphosphatase
Fru-6-P,2-kinase
Fru-kinase-Fru-bisphosphatase
Fructose 2,6-bisphosphatase
Fructose-2,6-bisphosphatase
Fructose-2,6-bisphosphate 2-phosphatase
Fructose-6-P,2-kinase
Fructose-6-phosphate,2-kinase
Fructose-6-phosphate,2-kinase-fructose-2,6-bisphosphatase
Phosphofructokinase 2
fructose-2,6-diphosphatase
An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.
See Also