Pro-Opiomelanocortin
Synonyms
ACTH Endorphin Precursor
ACTH beta Lipotropin Precursor
ACTH-Endorphin Precursor
ACTH-beta-Lipotropin Precursor
Corticotropin beta Lipotropin Precursor
Corticotropin-beta-Lipotropin Precursor
Endorphin ACTH Precursor
Endorphin-ACTH Precursor
Opiocortin
Opiomelanocortin, pro-
POMC
Pre POMC
Pre pro opiocortin
Pre-POMC
Pre-pro-opiocortin
Preproopiomelanocortin
Pro ACTH Endorphin
Pro Opio Melanocortin
Pro Opiocortin
Pro Opiomelanocortin
Pro-ACTH-Endorphin
Pro-Opio-Melanocortin
Pro-Opiocortin
Proopiocortin
Proopiomelanocortin
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).