Protein Footprinting
Synonyms
Footprint, Protein
Footprinting, Protein
Footprints, Protein
Protein Footprint
Protein Footprints
A method for determining points of contact between interacting proteins or binding sites of proteins to nucleic acids. Protein footprinting utilizes a protein cutting reagent or protease. Protein cleavage is inhibited where the proteins, or nucleic acids and protein, contact each other. After completion of the cutting reaction, the remaining peptide fragments are analyzed by electrophoresis.