Prothrombin

Synonyms

Blood Coagulation Factor II

Blood-coagulation factor II

Coagulation Factor II

Differentiation Reversal Factor

Factor II

Factor II, Coagulation

Factor, Differentiation Reversal

II, Coagulation Factor

A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.

See Also