Proto-Oncogene Proteins c-abl
Synonyms
Products, abl Proto-Oncogene
Proteins abl, Proto-Oncogene
Proto Oncogene Proteins abl
Proto Oncogene Proteins c abl
Proto-Oncogene Products, abl
Proto-Oncogene Proteins abl
Proto-Oncogene Proteins, abl
abl Proto Oncogene Products
abl Proto Oncogene Proteins
abl Proto-Oncogene Products
abl Proto-Oncogene Proteins
abl, Proto-Oncogene Proteins
c abl Proteins
c-abl Proteins
c-abl, Proto-Oncogene Proteins
Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.
See Also