Fusion Proteins, bcr-abl
Synonyms
Bcr Abl Tyrosine Kinase
Bcr-Abl Tyrosine Kinase
Fusion Proteins, bcr abl
Kinase, Bcr-Abl Tyrosine
Oncogene Protein p185(bcr-abl)
Oncogene Protein p190(bcr-abl)
Oncogene Protein p210(bcr-abl)
Oncogene Protein p230(bcr-abl)
Tyrosine Kinase, Bcr-Abl
bcr abl Fusion Proteins
bcr-abl Fusion Proteins
p185(bcr-abl) Fusion Proteins
p190(bcr-abl) Fusion Proteins
p210(bcr-abl) Fusion Proteins
p230(bcr-abl) Fusion Proteins
Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. Several different variants of the bcr-abl fusion proteins occur depending upon the precise location of the chromosomal breakpoint. These variants can be associated with distinct subtypes of leukemias such as PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; and NEUTROPHILIC LEUKEMIA, CHRONIC.
See Also