Proto-Oncogene Proteins c-kit
Synonyms
Antigens, CD117
CD117 Antigen
CD117 Antigens
Proto Oncogene Protein c kit
Proto Oncogene Protein kit
Proto Oncogene Proteins c kit
Proto-Oncogene Protein c-kit
Proto-Oncogene Protein kit
Proto-Oncogene Protein, kit
Receptor, Stem Cell Factor
SCF Receptor
Stem Cell Factor Receptor
c kit Protein
c kit Receptor
c-kit Protein
c-kit Receptor
c-kit, Proto-Oncogene Protein
c-kit, Proto-Oncogene Proteins
c-kit, p145
kit Proto Oncogene Protein
kit Proto-Oncogene Protein
p145 c kit
p145 c-kit
p145(c-kit)
p145c kit
p145c-kit
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.
See Also