Pulmonary Surfactant-Associated Protein A

Synonyms

Pulmonary Surfactant Associated Protein A

SP A Protein

SP-A Protein

Surfactant Protein A

An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.