Receptor, IGF Type 1
Synonyms
IGF 1 Receptor
IGF I Receptor
IGF Type 1 Receptor
IGF-1 Receptor
IGF-1 Receptors
IGF-I Receptor
Insulin Like Growth Factor I Receptor
Insulin-Like-Growth Factor I Receptor
Receptor, IGF I
Receptor, IGF Type 1 alpha Subunit
Receptor, IGF Type 1 beta Subunit
Receptor, IGF-1
Receptor, IGF-I
Receptor, Insulin-Like Growth Factor I
Receptor, Insulin-Like Growth Factor Type 1
Receptors, IGF 1
Receptors, IGF-1
Receptors, Insulin-Like-Growth Factor I
A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.