Receptors, sigma
Synonyms
Opioid Receptors, sigma
Receptor, sigma
Receptors, Opioid, sigma
Receptors, sigma Opioid
sigma Opioid Receptors
sigma Receptor
sigma Receptors
A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.