Renin
Synonyms
Angiotensin Forming Enzyme
Angiotensin-Forming Enzyme
Angiotensinogenase
Big Renin
Cryorenin
Inactive Renin
Pre Prorenin
Pre-Prorenin
Preprorenin
Prorenin
Renin, Big
Renin, Inactive
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.