RNA Interference
Synonyms
Co Suppression
Co-Suppression
Cosuppression
Gene Silencing, Post Transcriptional
Gene Silencing, Post-Transcriptional
Gene Silencing, Posttranscriptional
Gene Silencings, Posttranscriptional
Interference, RNA
Post Transcriptional Gene Silencing
Post-Transcriptional Gene Silencing
Post-Transcriptional Gene Silencings
Posttranscriptional Gene Silencing
RNA Silencing
RNAi
Silencing, Post-Transcriptional Gene
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.