RNA, Small Interfering
Synonyms
Hairpin RNA, Short
Hairpin RNA, Small
Interfering RNA, Short
Interfering RNA, Small
Piwi Interacting RNA
Piwi-Interacting RNA
RNA, Piwi Interacting
RNA, Piwi-Interacting
RNA, Scan
RNA, Short Hairpin
RNA, Short Interfering
RNA, Small Hairpin
RNA, Small Scan
Repeat Associated siRNA
Repeat-Associated siRNA
Scan RNA
Scan RNA, Small
Short Hairpin RNA
Short Interfering RNA
Small Hairpin RNA
Small Interfering RNA
Small Scan RNA
Trans Acting siRNA
Trans-Acting siRNA
piRNA
scnRNA
shRNA
siRNA
siRNA, Repeat Associated
siRNA, Repeat-Associated
siRNA, Trans Acting
siRNA, Trans-Acting
tasiRNA
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.