Severe Combined Immunodeficiency
Synonyms
Bare Lymphocyte Syndrome
Bare Lymphocyte Syndromes
Combined Immunodeficiencies, Severe
Combined Immunodeficiency, Severe
Familial Reticuloendothelioses
Familial Reticuloendotheliosis
Immunodeficiencies, Severe Combined
Immunodeficiency Syndrome, Severe Combined
Immunodeficiency, Severe Combined
Immunologic Deficiency, Severe Combined
Lymphocyte Syndrome, Bare
Lymphocyte Syndromes, Bare
Omenn Syndrome
Omenn's Syndrome
Omenns Syndrome
Reticuloendothelioses, Familial
Reticuloendotheliosis, Familial
Severe Combined Immune Deficiency
Severe Combined Immunodeficiencies
Severe Combined Immunodeficiency Syndrome
Severe Combined Immunologic Deficiency
Syndrome, Bare Lymphocyte
Syndrome, Omenn
Syndrome, Omenn's
Syndromes, Bare Lymphocyte
Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).