Solute Carrier Family 12, Member 1
Synonyms
BSC1 Transport Protein
Bumetanide-Sensitive Sodium-(Potassium)-Chloride Cotransporter 2
Cotransporter, NKCC2
Cotransporter, SLC12A1
Kidney Specific Na K Cl Symporter
Kidney-Specific Na-K-Cl Symporter
NKCC2 Cotransporter
NKCC2 Protein
Na-K-Cl Symporter, Kidney-Specific
Protein, BSC1 Transport
Protein, NKCC2
Protein, SLC12A1
SLC12A1 Cotransporter
SLC12A1 Protein
Symporter, Kidney-Specific Na-K-Cl
Transport Protein, BSC1
Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE. Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME.
See Also