Sphingomyelin Phosphodiesterase

Synonyms

Sphingomyelin Cholinephosphohydrolase

Sphingomyelin Cleaving Enzyme

Sphingomyelin cholinephosphohydrolase

Sphingomyelinase

Sphingomyelinase C

An enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide (N-acylsphingosine) plus choline phosphate. A defect in this enzyme leads to NIEMANN-PICK DISEASE. EC 3.1.4.12.