Thiorphan
Synonyms
(3-Mercapto-2-benzylpropionyl)glycine
Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (+-)-
Thiorphan, (R)-Isomer
Thiorphan, (S)-Isomer
Tiorphan
A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.