Vascular Endothelial Growth Factor Receptor-1
Synonyms
FLT VEGF Receptor
FLT1 RTK
FLT1 Receptor Tyrosine Kinase
Proto Oncogene Protein flt
Proto-Oncogene Protein flt
Receptor, FLT VEGF
Tyrosine Kinase, fms-Like
VEGF Receptor flt 1 Protein
VEGF Receptor flt-1 Protein
VEGF Receptor, FLT
VEGFR-1
Vascular Endothelial Growth Factor Receptor 1
fms-Like Tyrosine Kinase
A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.