Aflatoxin B1
Synonyms
Aflatoxin B
Aflatoxin B1 Dihydrochloride, (6aR-cis)-Isomer
Aflatoxin B1, (6aR-cis)-Isomer, 14C-Labeled
Aflatoxin B1, (6aR-cis)-Isomer, 2H-Labeled
Aflatoxin B1, (6aR-cis)-Isomer, 3H-Labeled
Aflatoxin B1, cis(+,-)-Isomer
Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)-
HSDB 3453
HSDB-3453
HSDB3453
NSC 529592
NSC-529592
NSC529592
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.