Etoposide
Synonyms
Celltop
Demethyl Epipodophyllotoxin Ethylidine Glucoside
Eposide
Eposin
Eto GRY
Eto-GRY
Etomedac
Etopos
Etoposide Pierre Fabre
Etoposide Teva
Etoposide, (5S)-Isomer
Etoposide, (5a alpha)-Isomer
Etoposide, (5a alpha,9 alpha)-Isomer
Etoposide, alpha D Glucopyranosyl Isomer
Etoposide, alpha-D-Glucopyranosyl Isomer
Etoposido Ferrer Farma
Exitop
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 9-((4,6-O-ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-
Lastet
NSC 141540
NSC-141540
NSC141540
Onkoposid
Riboposid
Teva, Etoposide
Toposar
VP 16
VP 16 213
VP 16-213
VP 16213
VP-16
VP16
Vepesid
Vepeside Sandoz
Vepeside-Sandoz
alpha-D-Glucopyranosyl Isomer Etoposide
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.