G(M2) Activator Protein

Synonyms

Activator Protein, GM2

GM(2) Activating Protein

GM2 Activator Protein

Hexosaminidase Activator

An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT.