Genes, erbB-2
Synonyms
Gene, HER2
Gene, erbb2
Genes, HER-2
Genes, HER2
Genes, erbb2
Genes, neu
HER-2 Gene
HER-2 Genes
HER2 Gene
HER2 Genes
c erbB 2 Genes
c erbB 2 Proto Oncogenes
c-erbB-2 Gene
c-erbB-2 Genes
c-erbB-2 Proto-Oncogene
c-erbB-2 Proto-Oncogenes
erbB 2 Genes
erbB-2 Gene
erbB-2 Genes
erbb2 Gene
erbb2 Genes
neu Gene
neu Genes
The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.