Platelet Glycoprotein GPIb-IX Complex
Synonyms
Antigen, CD42a
Antigen, CD42b
Antigen, CD42c
Antigen, CD42d
Antigens, CD42a
Antigens, CD42b
Antigens, CD42c
Antigens, CD42d
CD42a Antigen
CD42a Antigens
CD42b Antigen
CD42b Antigens
CD42c Antigen
CD42c Antigens
CD42d Antigen
CD42d Antigens
Glycoprotein Ib
Glycoprotein Ib IX Complex
Glycoprotein Ib alpha
Glycoprotein Ib beta
Glycoprotein Ib-IX Complex
Platelet Glycoprotein GPIb IX Complex
Platelet Glycoprotein IX
Platelet Membrane Glycoprotein IX
Platelet Membrane Glycoprotein Ib
Platelet Membrane Glycoprotein V
Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.