Receptor, Fibroblast Growth Factor, Type 2
Synonyms
Antigen, CD332
BEK Fibroblast Growth Factor Receptor
BEK Fibroblast Growth Factor Receptor Kinase
BEK Protein Tyrosine Kinase
Bek Fgf Receptor Kinase
Bek Related Fibroblast Growth Factor Receptor 1
Bek-Related Fibroblast Growth Factor-Receptor-1
CD332 Antigen
FGFR2 Protein
FGFR2b
FGFR2c
Fibroblast Growth Factor Receptor 2
Fibroblast Growth Factor Receptor 2b
Fibroblast Growth Factor Receptor 2c
Fibroblast Growth Factor Receptors 2
Fibroblast Growth Factor Receptors 2b
Receptor, Fibroblast Growth Factor 2b
Receptor, Fibroblast Growth Factor 2c
A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).