Semaphorin-3A
Synonyms
Collapsin
Collapsin 1
Collapsin-1
Collapsing Factor
Sem D
Sema3A
Semaphorin 3A
Semaphorin D
The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.