Transforming Growth Factor beta2
Synonyms
BSC 1 Cell Growth Inhibitor
BSC-1 Cell Growth Inhibitor
Cartilage Inducing Factor B
Cartilage-Inducing Factor-B
Glioblastoma Derived T Cell Suppressor Factor
Glioblastoma-Derived T-Cell Suppressor Factor
Latency-Associated Protein, TGF-beta2
Polyergin
Suppressor Factor, T-Cell, Glioblastoma-Derived
TGF beta2 Latency Associated Protein
TGF beta2LAP
TGF-beta-2
TGF-beta2
TGF-beta2 Latency-Associated Protein
TGF-beta2LAP
Transforming Growth Factor beta 2 Latency Associated Peptide
A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.